Publications
Below you find a list of the key publications
Andreatta F, Hendriks D*,#, Artegiani B*,#
*Equal contribution, #Corresponding author
Human organoids as an emerging tool for genome screenings
Annual Review of Biomedical Engineering, 2025
Artegiani B*,#, Hendriks D*,#.
*Equal contribution, #Corresponding author
Organoids from pluripotent stem cells and human tissues: When two cultures meet each other
Developmental Cell, 2025
Pagliaro A$, Andreatta F$, Finger R$, Artegiani B*,#, Hendriks D*,#.
$Co-first author
*Equal contribution, #Corresponding author
Generation of human fetal brain organoids and their CRISPR engineering for brain tumor modeling
Nature Protocols, 2025
Pagliaro A, Artegiani B*,#, Hendriks D*,#.
*Equal contribution, #Corresponding author
Emerging approaches to enhance human brain organoid physiology
Trends in Cell Biology, 2025
Hendriks D*,#, Artegiani B*,#, Margaritis T, Zoutendijk I, Chuva de Sousa Lopes S, Clevers H#.
*Equal contribution, #Corresponding author
Mapping of mitogen and metabolic sensitivity in organoids defines requirements for human hepatocyte growth.
Nature Communications, 2024
Hendriks D*,#, Pagliaro A$, Andreatta F$, Ma Z, van Giessen J, Massalini S, López-Iglesias C, van Son G, DeMartino J, Damen M, Zoutendijk I, Staliarova N, Bredenoord A, Holstege F, Peters P, Margaritis T, Chuva de Sousa Lopes S, Wu W, Clevers H*,#, Artegiani B*,#.
$Co-second author
*Senior author, #Corresponding author
Human fetal brain self-organizes into long-term expanding organoids.
Cell, 2024
Pagliaro A, Finger R, Zoutendijk I, Bunschuh S, Clevers H, Hendriks D*,#, Artegiani B*,#.
*Co-last author, #Corresponding author
Temporal morphogen gradient-driven neural induction shapes single expanded neuroepithelium brain organoids with enhanced cortical identity.
Nature Communications, 2023
Rüland L, Andreatta F, Massalini S, Chuva de Sousa Lopes S, Clevers H, Hendriks D*,#, Artegiani B*,#.
*Co-last author, #Corresponding author
Organoid models of fibrolamellar carcinoma mutations reveal hepatocyte trans-differentiation through cooperative BAP1 and PRKAR2A loss.
Nature Communications, 2023
Hendriks D#, Brouwers J, Hamer K, Geurts M, Luciana L, Massalini S, López-Iglesias C, Peters P, Rodríguez-Colman M, Chuva de Sousa Lopes S, Artegiani B*,#, Clevers H*,#.
*Co-last author, #Corresponding author
Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis.
Nature Biotechnology, 2023
Hendriks D*,#, Artegiani B*,#, Hu H, Chuva de Sousa Lopes S, Clevers H.
*Co-first author, #Corresponding author
Establishment of human fetal hepatocyte organoids and CRISPR-Cas9-based gene knockin and knockout organoid cultures from human liver.
Nature Protocols, 2021
Hendriks D, Clevers H, Artegiani B.
CRISPR-Cas tools and their application in genetic engineering of human stem cells and organoids.
Cell Stem Cell, 2020
Artegiani B*, Hendriks D*, Beumer J, Kok R, Zheng X, Joore I, Chuva de Sousa Lopes S, van Zon J, Tans S, Clevers H.
*Co-first author
Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing.
Nature Cell Biology, 2020
